What is Oxycodone?

Oxycodone is a short-acting opioid. Oxycodone relieves pain for about four to six hours, so it needs to be given 4 to 6 times a day to provide pain relief for the whole day. Oxycodone works by binding to specific receptors in the brain known as opioid receptors.

The medicine is relatively selective for a type of opioid receptor, that is, the mu-opioid receptor. Oxycodone is a complete agonist at the mu receptor, meaning that it does not have a ceiling effect for pain relief. The risk of side effects, like CNS and respiratory depression, rises with higher doses, and the chances of overdosage increase.

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Uses of Oxycodone

This medication is usually given for acute pain, like that following trauma or surgery.  Oxycodone is given to relieve moderate-to-severe pain.

Higher dosages of Oxycodone are taken for increased pain relief. Oxycodone extended capsules and Oxycodone extended-release tablets are used to control severe pain in patients expected to require pain medicines around the clock for a considerable amount of time and can’t be treated with other medication.

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Important Information

It would help if you remembered that you should only use Oxycodone for severe pain when non-opioid medicine does not help, or you can not tolerate it. One should only take a high dosage( above 40 mg per tablet) of the drug if the person has frequently been taking moderate amounts of opioid pain-relief medicines.

A large dosage of Oxycodone can also cause overdose or even death. You should, therefore, avoid taking Oxycodone for mild pain. Order Oxycodone 20mg online from us to ensure that you get a superior quality product.

What should I do before using Oxycodone?

Do not take Oxycodone if:

• You have lung-related problems or experience trouble breathing;
• Kidney or liver disease;
• Sleep apnea;
• Urination issues;
• Thyroid;
• Problems in the pancreas or gallbladder;
• You have breathing problems, seizures, or a head injury;
• Drug or alcohol addiction.

Children below eleven years of age should not be given Oxycodone.

How should I take Oxycodone?

One can buy Oxycodone online overnight and take it with or without food. Patients usually take it every four to six hours. In case you experience nausea, you must take this medicine with food. You can discuss with your doctor other techniques to control nausea.

It would be best to swallow whole Oxycodone tablets and not crush, chew, break, or dissolve them, leading to Oxycodone overdose by releasing all of the medicine at once. Take only a single Oxycodone tablet at a time to ensure you do not choke if your prescribed dosage is for more than one tablet.

Oxycodone dosages

• You should take Oxycodone tablets at an interval of 4 to 6 hours. The dosage depends on the patient’s previous history of requirements for analgesia. Order Oxycodone 40mg online as per the dosage that best suits you.
• The usual starting dose for patients who have not taken any opioids in the past or patients with severe pain unmanageable by opioids of lower strength is 10 mg.
• Some patients can benefit from an initial dose of 5 mg to reduce the occurrence of side effects. Oxycodone should not be used in minor patients.
• Oxycodone 120 mg, 80 mg, and 60 mg tablets should not be used in patients not previously exposed to opioids. These tablet strengths may cause dangerous respiratory depression when given to opioid naïve patients.
• Before starting treatment with Oxycodone, doctors must discuss with patients and put a strategy to end therapy with Oxycodone to reduce the possible risk of drug withdrawal syndrome.
• Usually, the minimum effective dosage for analgesia should be selected. With the increased severity of pain, the dosage of Oxycodone tablets should be increased, using the different tablet strengths to achieve pain relief in patients. The correct dosage for any patient is that which controls the pain for a total of twelve hours.
• Patients must be titrated for pain relief unless uncontrolled extreme drug reactions prevent this. If there is a necessity for higher doses, increments of 25% – 50% should be made.

What should I avoid while taking Oxycodone?

• One should not drink alcohol during the treatment with Oxycodone because that may increase the risk of experiencing adverse side effects.
• Another essential thing to know is that Oxycodone may cause severe breathing problems, especially during consumption’s first or second day.
• Also, share with your doctor if you are pregnant or are planning to be pregnant because Oxycodone could lead to severe withdrawal symptoms in the baby.
• Inform the baby’s doctor immediately if the baby experiences any of these symptoms- hyperactivity, uncontrolled shaking, abnormal sleep, diarrhea, failure to gain weight or vomiting. It would be best to avoid consuming grapefruit in any form while you are on this medication.
• Discuss with your doctor before doing so. The doctor prescribes the dosage according to your condition and response to the medication. Please do not increase the dosage or take it any longer than the doctor has prescribed.
• Stop taking the drug when directed to do so. If you stop taking Oxycodone suddenly, you may experience withdrawal symptoms. Therefore, you must strictly follow your doctor’s instructions regarding the same.
• Inform your doctor if you have any symptoms such as mental changes, runny nose, muscle aches, trouble sleeping, anxiety, sweating, or sudden changes in behavior.

What drugs can interact with Oxycodone?

Check with your doctor before taking over-the-counter medication if you are taking Oxycodone. Many over-the-counter medications may cause dangerous drug interactions with Oxycodone. Medicines like diphenhydramine, found in some allergy and cold medications, may cause sedative effects. These medicines can be harmful when added to the sedative side effects of Oxycodone.

While many medicines can interact with Oxycodone, some examples are:

• Anti-seizure medications, like topiramate (Topamax, Qudexy XR, others), carbamazepine (Carbatrol, Tegretol, others), and lamotrigine (Lamictal)
• alcohol
• Benzodazepines, such as clonazepam (Klonopin), diazepam (Valium), alprazolam (Xanax), and lorazepam (Ativan)
• Certain antibiotics like clarithromycin
• Some antidepressants
• Certain antifungals, including an ketoconazole ,voriconazole (Vfend), itraconazole (Onmel, Tolsura), and voriconazole (Vfend)
• Some antiretroviral medications used for HIV infection, including ritonavir (Norvir), atazanavir, and indinavir (Crixivan)
• Medication for sleeping problems, like zolpidem, eszopiclone, and zaleplon
• Medicines used to treat psychiatric problems, like haloperidol, clozapine, aripiprazole, and quetiapine
• Drugs used to treat nerve pain, like gabapentin and pregabalin
• Muscle relaxers, like cyclobenzaprine and baclofen
• Some other opioid medicines

What are the possible side effects of Oxycodone?

Respiratory depression is likely to happen during the first one to three days of Oxycodone medication, after a dosage rise, or if a high amount of Oxycodone is taken.

Children, older people, or those with existing respiratory conditions are likely to be more at risk. Respiratory depression can cause death.

Stopping Oxycodone suddenly in a person who has become physically dependent on it may lead to withdrawal symptoms like irritability, pupil dilation, restlessness, a runny nose, watery eyes, muscle aches, sweating, insomnia, gastrointestinal complaints like vomiting, abdominal pain, diarrhea, or nausea.

Get emergency medical help if you show allergic reaction symptoms to Oxycodone: difficulty breathing, hives, swelling of your throat, lips, face, or tongue.

Opioid medicine can lead to breathlessness and even death. A person caring for you must seek emergency medical attention or give naloxone if you have difficulty breathing, if you are hard to wake up, or have blue-colored lips.

Call your doctor immediately if you have:

• Noisy breathing, breathing that stops during sleep, sighing, shallow breathing;
• a slow heart rate;
• a light-headed feeling;
• confusion, or unusual thoughts;
• seizure;
• low cortisol levels or
• High levels of serotonin in the body.